Trichoplein, Keratin Filament Binding (TCHP) (C-Term) Peptide
TCHP
适用: 人
宿主: 合成
BP, WB
产品编号 ABIN984916
发货至:
中国
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Contact Info
Our Local Distributor
中国
北京 101111
北京 101111
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Beijing Economic Technological Development Area
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Quick Overview for Trichoplein, Keratin Filament Binding (TCHP) (C-Term) Peptide (ABIN984916)
抗原
TCHP
(Trichoplein, Keratin Filament Binding (TCHP))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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蛋白结构域
- C-Term
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序列
- IQEKIEQNRR AQEESLKHRE QLIRNLEEVR ELARREKEES EKLKSARKQE
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产品特性
- This is a synthetic peptide designed for use in combination with anti-TCHP Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- TCHP (Trichoplein, Keratin Filament Binding (TCHP))
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背景
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TCHP is a tumor suppressor which has the ability to inhibit cell growth and be pro-apoptotic during cell stress. It inhibits cell growth in bladder and prostate cancer cells by a down-regulation of HSPB1 by inhibiting its phosphorylation. It may act as a 'capping' or 'branching' protein for keratin filaments in the cell periphery. And it also may regulate K8/K18 filament and desmosome organization mainly at the apical or peripheral regions of simple epithelial cells.
Alias Symbols: MGC10854, TpMs
Protein Interaction Partner: CCDC85B,KRT14,KRT15,KRT16,KRT18,KRT5,KRT6A,KRT8,NME7,TEX11,VIM,CCDC85B,KRT15,NME7,TEX11,VIM
Protein Size: 498 -
分子量
- 61 kDa
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基因ID
- 84260
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NCBI登录号
- NM_032300, NP_115676
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UniProt
- Q9BT92
抗原
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