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Transcription Factor 7-Like 2 (T-Cell Specific, HMG-Box) (TCF7L2) Peptide

TCF7L2 适用: 人 宿主: 合成 BP, WB
产品编号 ABIN984909
发货至: 中国
  • 抗原 See all TCF7L2 products
    TCF7L2 (Transcription Factor 7-Like 2 (T-Cell Specific, HMG-Box) (TCF7L2))
    宿主
    资源
    • 3
    合成
    应用范围
    Blocking Peptide (BP), Western Blotting (WB)
    产品特性
    This is a synthetic peptide designed for use in combination with anti-TCF7L2 antibody (Catalog #: ARP33414_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    纯化方法
    Purified
  • 应用备注
    Each Investigator should determine their own optimal working dilution for specific applications.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    浓度
    1 mg/mL
    缓冲液
    Final peptide concentration is 1 mg/mL in PBS.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原
    TCF7L2 (Transcription Factor 7-Like 2 (T-Cell Specific, HMG-Box) (TCF7L2))
    别名
    TCF4B Peptide, TCF4E Peptide, Tcf-4 Peptide, Tcf4 Peptide, mTcf-4B Peptide, mTcf-4E Peptide, tcf4 Peptide, XTCF-4 Peptide, tcf4e Peptide, TCF4 Peptide, TCF-4 Peptide, TCFL2 Peptide, transcription factor 7 like 2 Peptide, transcription factor 7-like 2 Peptide, transcription factor 7 like 2, T cell specific, HMG box Peptide, transcription factor 7 like 2 L homeolog Peptide, transcription factor 7-like 2 (T-cell specific, HMG-box) Peptide, TCF7L2 Peptide, LOC100545943 Peptide, Tcf7l2 Peptide, tcf7l2 Peptide, tcf7l2.L Peptide
    背景
    The TCL7L2 is a high mobility group (HMG) box-containing transcription factor implicated in blood glucose homeostasis. The study of Yi et al. suggested that TCL7L2 acts through regulation of proglucagon through repression of the proglucagon gene in enteroendocrine cells via the Wnt signaling pathway. The TCL7L2 gene product is a high mobility group (HMG) box-containing transcription factor implicated in blood glucose homeostasis. The study of Yi et al. (2005) [PubMed 15525634] suggested that TCL7L2 acts through regulation of proglucagon (MIM 138030) through repression of the proglucagon gene in enteroendocrine cells via the Wnt signaling pathway.[supplied by OMIM]. Sequence Note: This gene (TCF7L2, alias TCF-4) is distinct from TCF4. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-202 DA473655.1 1-202 203-251 Y11306.2 3-51 252-1252 AK225809.1 256-1256 1253-1305 Y11306.2 1053-1105 1306-1756 AK225809.1 1310-1760 1757-1811 Y11306.2 1557-1611 1812-2652 AK225809.1 1765-2605

    Alias Symbols: TCF-4, TCF4

    Protein Interaction Partner: CTBP1,CTNNB1,CTNNB1,RAC1,CSNK2A1,CSNK2A2,CTNNB1,CTNNBIP1,DAXX,EP300,JUP,PSEN1,CTNNB1,JUP,NLK,PSEN1

    Protein Size: 596
    分子量
    65 kDa
    基因ID
    6934
    NCBI登录号
    NM_030756, NP_110383
    UniProt
    Q6FHW4
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