HNF1 Homeobox B (HNF1B) Peptide
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Quick Overview for HNF1 Homeobox B (HNF1B) Peptide (ABIN984890)
抗原
宿主
资源
应用范围
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产品特性
- This is a synthetic peptide designed for use in combination with anti-TCF2 antibody (Catalog #: ARP32320_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- HNF1B (HNF1 Homeobox B (HNF1B))
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背景
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TCF2 encodes transcription factor 2, a liver-specific factor of the homeobox-containing basic helix-turn-helix family. The TCF2 protein is believed to form heterodimers with another liver-specific member of this transcription factor family, TCF1, depending on the TCF2 isoform, the result may be to activate or inhibit transcription of target genes. Mutation of TCF2 that disrupts normal function has been identified as the cause of MODY5 (Maturity-Onset of Diabetes, Type 5).
Alias Symbols: FJHN, HNF1beta, HNF2, LFB3, MODY5, TCF2, VHNF1, HPC11, LF-B3
Protein Interaction Partner: ATF1,CREBBP,HNF1A,ATF1,CREB1,HNF1A
Protein Size: 399 -
分子量
- 45 kDa
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基因ID
- 6928
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NCBI登录号
- NM_006481, NP_006472
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UniProt
- P35680
抗原
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