SWAP Switching B-Cell Complex 70kDa Subunit (SWAP70) Peptide
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Quick Overview for SWAP Switching B-Cell Complex 70kDa Subunit (SWAP70) Peptide (ABIN984655)
抗原
宿主
资源
应用范围
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产品特性
- This is a synthetic peptide designed for use in combination with anti-SWAP70 antibody (Catalog #: ARP46214_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- SWAP70 (SWAP Switching B-Cell Complex 70kDa Subunit (SWAP70))
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背景
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Phosphatidylinositol 3,4,5-trisphosphate-dependent guanine nucleotide exchange factor (GEF) which, independently of RAS, transduces signals from tyrosine kinase receptors to RAC. SWAP70 also mediates signaling of membrane ruffling. It regulates the actin cytoskeleton as an effector or adapter protein in response to agonist stimulated phosphatidylinositol (3,4)-bisphosphate production and cell protrusion.
Alias Symbols: FLJ39540, HSPC321, KIAA0640, SWAP-70
Protein Interaction Partner: CELSR3,IGHG1,PARP1,NCL,NPM1,PARP1
Protein Size: 585 -
分子量
- 69 kDa
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基因ID
- 23075
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NCBI登录号
- NM_015055, NP_055870
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UniProt
- Q9UH65
抗原
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