Small Ubiquitin Related Modifier 3 (SUMO3) (N-Term) Peptide
SUMO3
适用: 小鼠
宿主: 合成
BP, WB
产品编号 ABIN984626
发货至:
中国
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Contact Info
Our Local Distributor
中国
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Quick Overview for Small Ubiquitin Related Modifier 3 (SUMO3) (N-Term) Peptide (ABIN984626)
抗原
SUMO3
(Small Ubiquitin Related Modifier 3 (SUMO3))
宿主
小鼠
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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蛋白结构域
- N-Term
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序列
- DQEAKPSTED LGDKKEGEYI KLKVIGQDSS EIHFKVKMTT HLKKLKESYC
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产品特性
- This is a synthetic peptide designed for use in combination with anti-Sumo1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- SUMO3 (Small Ubiquitin Related Modifier 3 (SUMO3))
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背景
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Ubiquitin-like protein that can be covalently attached to proteins as a monomer or a lysine-linked polymer. Covalent attachment via an isopeptide bond to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by E3 ligases such as PIAS1-4, RANBP2 or CBX4. This post-translational modification on lysine residues of proteins plays a crucial role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. It is involved for instance in targeting RANGAP1 to the nuclear pore complex protein RANBP2. Polymeric SUMO1 chains are also susceptible to polyubiquitination which functions as a signal for proteasomal degradation of modified proteins. It may also regulate a network of genes involved in palate development.
Alias Symbols: GMP1, MGC103203, PIC1, SENTRIN, SMT3, SMT3H3, SMTP3, SUMO-1, Smt3C, Ubl1
Protein Interaction Partner: Jun,Junb,Hif1a,Nfkb2,Pou5f1
Protein Size: 101 -
分子量
- 11 kDa
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基因ID
- 22218
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NCBI登录号
- NM_009460, NP_033486
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UniProt
- P63166
抗原
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