Stanniocalcin 2 (STC2) (C-Term) Peptide
STC2
适用: 人
宿主: 合成
BP, WB
Quick Overview for Stanniocalcin 2 (STC2) (C-Term) Peptide (ABIN984546)
抗原
Stanniocalcin 2 (STC2)
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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蛋白结构域
- C-Term
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序列
- PSSRETGRGA KGERGSKSHP NAHARGRVGG LGAQGPSGSS EWEDEQSEYS
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产品特性
- This is a synthetic peptide designed for use in combination with anti-STC2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Stanniocalcin 2 (STC2)
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背景
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This gene encodes a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. The encoded protein has 10 of its 15 cysteine residues conserved among stanniocalcin family members and is phosphorylated by casein kinase 2 exclusively on its serine residues. Its C-terminus contains a cluster of histidine residues which may interact with metal ions. The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. Constitutive overexpression of human stanniocalcin 2 in mice resulted in pre- and postnatal growth restriction, reduced bone and skeletal muscle growth, and organomegaly. Expression of this gene is induced by estrogen and altered in some breast cancers.
Alias Symbols: STC-2, STCRP
Protein Interaction Partner: ADAM11,AIFM1,ARHGEF40,ARRB2,CARHSP1,EIF2B3,PEBP1,POLR2C,POLR3F,PPP1R8,PTN,ADAM11,AIFM1,ARHGEF40,ARRB2,CARHSP1,EIF2B3,PEBP1,POLR2C,POLR3F,PPP1R8,PTN
Protein Size: 302 -
分子量
- 31 kDa
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基因ID
- 8614
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NCBI登录号
- NM_003714, NP_003705
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UniProt
- O76061
抗原
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