Proto-oncogene tyrosine-protein kinase Src (Src) (N-Term) Peptide
Src
适用: 人
宿主: 合成
BP, WB
产品编号 ABIN984405
发货至:
中国
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Contact Info
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中国
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Quick Overview for Proto-oncogene tyrosine-protein kinase Src (Src) (N-Term) Peptide (ABIN984405)
抗原
Src
(Proto-oncogene tyrosine-protein kinase Src (Src))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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蛋白结构域
- N-Term
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产品特性
- This is a synthetic peptide designed for use in combination with anti-SRC antibody (Catalog #: ARP32476_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Src (Proto-oncogene tyrosine-protein kinase Src (Src))
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物质类
- Viral Protein
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背景
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This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. SRC protein is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer.This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene.
Alias Symbols: ASV, SRC1, c-SRC, p60-Src
Protein Interaction Partner: E2F4,ABL1,BCAR1,BCR,CDCP1,DRD4,ERBB2,ETS1,ETS2,GJA1,GJB1,HNRNPK,KHDRBS1,MUC1,PDE4D,PDGFRB,PTK2,PTK2,PTPN2,RGS16,SHB,SHC1,SRC,ABL1,ACTN1,ADAM12,ADAM15,ADRB2,ADRB3,ADRBK1,AFAP1,AFAP1L2,AKT1,ANKRD11,ANXA1,ANXA2,AR,ARHGAP1,ARHGAP32,ARR3,ASAP1,ATP2B4,AXL,BCAR1,BCR,BMX,CAV1,CAV2,CBL,CBLC,CD2AP,CD33,CD36,CD46,CD59,CDCP1,CDH5,CDK5,CDKN1B,CEACAM1,CEACAM3,CHUK,CNTNAP1,CSK,CTNNB1,CTNND1,CTTN,DAB1,DAB2,DAG1,DAPP1,DDR2,DGKA,DGKZ,DLG4,DNM1,DNM2,DOK1,DOK2,DOK4,EFNB1,EFNB2,EGFR,EPHB2,EPS8,ERBB2,ESR1,ESR2,ETS1,ETS2,EVL,FARP2,FASLG,FGR,FHIT,FOXO1,FRS2,FYB,GAB2,GAB3,GFAP,GIT1,GJA1,GJB1,GNB2L1,GRB10,GRB2,GRIN2A,GRIN2B,GRLF1,GTF2I,GUCY2C,HLA-A,HLA-B,HNF1A,HNRNPK,HRAS,HSP90AA1,IGF1R,IKBKB,IKBKG,IL6R,INPPL1,INSR,ITGB3,JUP,KCNA5,KCNB1,KCNQ5,KDR,KHDRBS1,KIFAP3,KIT,LRP1,MAPK15,MATK,MED28,MET,MPZL1,MST1R,MUC1,MYLK,ND2,NFKBIA,NMT1,NOS2,NPHS1,NR1I2,P2RY2,PAK2,PDCD6IP,PDE6G,PDGFRB,PDPK1,PECAM1,PGR,PIK3R1,PKD1,PLCG1,PPARD,PPP2R4,PRKACA,PRKCA,PRKCD,PRKCE,PRKCH,PRKCI,PRKCZ,PRKD1,PTK2,PTK2B,PTPN1,PTPN11,PTPN18,PTPN2,PTPN21,PTPN6,PTPRA,PTPRE,PXN,RAF1,RASA1,RET,RGS16,RXRA,SH2D3C,SH3BP1,SH3PXD2A,SHB,SHC1,SKAP1,SLC9A2,SMARCB1,SMARCE1,SPTAN1,SRC,SRF,STAP2,STAT1,STAT3,STAT5A,STAT5B,STAT6,SYK,SYN1,TERT,THRA,TIAM1,TNFRSF11A,TRAF1,TRAF3,TRAF6,TRAT1,TRIP10,TRIP6,TRPC6,TRPV4,TUB,TXK,TYRO3,VCL,VIL1,WAS,WBP11,WWOX,YTHDC1,YWHAB,YWHAE,YWHAG,YWHAH,ABL1,ADRB2,ADRB3,ADRBK1,AHR,AR,ARHGAP1,ARHGAP17,ARHGAP32,ARHGAP32,ARNT,ARR3,ASAP1,ASAP2,AXL,Adrb3,BCAR1,BMX,CAV1,CAV2,CBL,CD44,CD46,CDC25C,CDC37,CDH1,CRK,CSF1R,CSK,CTNND1,DAB2,DAG1,DDR2,DOCK1,DOK1,DOK4,EFNB1,EGFR,EP300,EPHA3,EPHA4,EPHB2,EPS8,ERBB2,ESR1,ESR2,EVL,FOXO1,FYN,GAB2,GAB3,GNB2L1,GRB10,GRB2,GRIN2A,GSN,HNF1A,HSP90AA1,ITK,KHDRBS1,KIFAP3,LRP1,LYN,MAP2,MAPK8IP3,MATK,MET,MICAL1,MPZL1,MUC1,MYLK,NCOA6,ND2,PDE6G,PECAM1,PELP1,PIK3R1,PLCG1,PLD1,PLD2,PLSCR1,PRKCZ,PTK2,PTK2B,PTPN21,PTPRA,PXN,RAF1,RARA,RASA1,RET,RPL10,RPS6KB1,RPS6KB2,RXRA,SH3BP1,SHB,SKAP1,SLC9A2,SNURF,SRF,STAT1,STAT3,SYK,SYN1,THRB,TNFSF11,TRAF1,TRAF3,TRAF6,TRIP4,TRIP6,TRPC6,TRPV4,TYRO3,WAS
Protein Size: 536 -
分子量
- 60 kDa
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基因ID
- 6714
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NCBI登录号
- NM_005417, NP_005408
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UniProt
- P12931
抗原
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