serine Palmitoyltransferase, Long Chain Base Subunit 1 (SPTLC1) (Middle Region) Peptide
SPTLC1
适用: 人
宿主: 合成
BP, WB
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- 抗原 See all SPTLC1 products
- SPTLC1 (serine Palmitoyltransferase, Long Chain Base Subunit 1 (SPTLC1))
- 蛋白结构域
- Middle Region
- 宿主
- 人
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资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB)
- 产品特性
- This is a synthetic peptide designed for use in combination with anti-SPTLC1 antibody (Catalog #: ARP46722_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- 纯化方法
- Purified
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- 应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 浓度
- 1 mg/mL
- 缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- 抗原
- SPTLC1 (serine Palmitoyltransferase, Long Chain Base Subunit 1 (SPTLC1))
- 背景
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Serine palmitoyltransferase, which consists of two different subunits, is the key enzyme in sphingolipid biosynthesis. It converts L-serine and palmitoyl-CoA to 3-oxosphinganine with pyridoxal 5'-phosphate as a cofactor. SPTLC1 is the long chain base subunit 1 of serine palmitoyltransferase. Mutations in SPTLC1 gene were identified in patients with hereditary sensory neuropathy type 1. Serine palmitoyltransferase, which consists of two different subunits, is the key enzyme in sphingolipid biosynthesis. It converts L-serine and palmitoyl-CoA to 3-oxosphinganine with pyridoxal 5'-phosphate as a cofactor. The product of this gene is the long chain base subunit 1 of serine palmitoyltransferase. Mutations in this gene were identified in patients with hereditary sensory neuropathy type 1. Alternatively spliced variants encoding different isoforms have been identified.
Alias Symbols: HSAN, HSAN1, HSN1, LBC1, LCB1, MGC14645, SPT1, SPTI, hLCB1
Protein Interaction Partner: ABCA1,SPTLC2,C20orf24,MAGED1,ORMDL3,RGS20
Protein Size: 473 - 分子量
- 53 kDa
- 基因ID
- 10558
- NCBI登录号
- NM_006415, NP_006406
- UniProt
- O15269
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