Sortilin 1 (SORT1) (C-Term) Peptide
SORT1
适用: 人
宿主: 合成
BP, WB
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- 抗原 See all Sortilin 1 (SORT1) products
- Sortilin 1 (SORT1)
- 蛋白结构域
- C-Term
- 宿主
- 人
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资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB)
- 序列
- YVCGGRFLVH RYSVLQQHAE ANGVDGVDAL DTASHTNKSG YHDDSDEDLL
- 产品特性
- This is a synthetic peptide designed for use in combination with anti-SORT1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- 纯化方法
- Purified
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- 应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 浓度
- 1 mg/mL
- 缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- 抗原
- Sortilin 1 (SORT1)
- 别名
- SORT1 Peptide, 19.m02079 Peptide, gp95 Peptide, ldlcq6 Peptide, sortilin Peptide, Gp95 Peptide, LDLCQ6 Peptide, NT3 Peptide, 2900053A11Rik Peptide, AI852375 Peptide, Ntr3 Peptide, Ntsr3 Peptide, Nt3 Peptide, Nts3 Peptide, sort1 Peptide, zgc:85953 Peptide, sortilin 1 Peptide, sortilin Peptide, sortilin 1 S homeolog Peptide, sortilin 1a Peptide, SORT1 Peptide, TP01_0016 Peptide, BBOV_I002730 Peptide, sort1.S Peptide, Sort1 Peptide, sort1a Peptide
- 背景
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This gene encodes a protein that is a multi-ligand type-1 receptor with similarity to the yeast carboxypeptidase Y sorting receptor Vps10 protein. The encoded protein, a trans-Golgi network (TGN) transmembrane protein, binds a number of unrelated ligands that participate in a wide range of cellular processes, however, it lacks the typical features of a signalling receptor. In the TGN, furin mediates the activation of the mature binding form. The encoded protein consists of a large luminal domain, a single transmembrane segment and short C-terminal cytoplasmic tail. The luminal domain contains a cysteine-rich region similar to two corresponding segments in the yeast Vps10p, the cytoplasmic tail is similar to the corresponding segment of the cation-independent mannose 6-phosphate receptor and the tail also interacts with the VHS domains of GGA (Golgi-associated, gamma-adaptin homologous, ARF-interacting) proteins.
Alias Symbols: Gp95, NT3
Protein Interaction Partner: NGFR,SLC2A4,BDNF,GGA1,GGA2,LRPAP1,NGF,NGFR,NTS,CDK2,GGA1,GGA2,LRPAP1,NGF
Protein Size: 831 - 分子量
- 84 kDa
- 基因ID
- 6272
- NCBI登录号
- NM_002959, NP_002950
- UniProt
- Q99523
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