Sortilin 1 (SORT1) (C-Term) Peptide
SORT1
适用: 人
宿主: 合成
BP, WB
Quick Overview for Sortilin 1 (SORT1) (C-Term) Peptide (ABIN984238)
抗原
Sortilin 1 (SORT1)
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
-
-
蛋白结构域
- C-Term
-
序列
- YVCGGRFLVH RYSVLQQHAE ANGVDGVDAL DTASHTNKSG YHDDSDEDLL
-
产品特性
- This is a synthetic peptide designed for use in combination with anti-SORT1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
-
纯化方法
- Purified
-
-
Sortilin 1 (SORT1) peptide
SORT1 宿主: 合成 BP, WB, IHC
-
-
应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
-
浓度
- 1 mg/mL
-
缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
-
注意事项
- Avoid repeated freeze-thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
-
- Sortilin 1 (SORT1)
-
背景
-
This gene encodes a protein that is a multi-ligand type-1 receptor with similarity to the yeast carboxypeptidase Y sorting receptor Vps10 protein. The encoded protein, a trans-Golgi network (TGN) transmembrane protein, binds a number of unrelated ligands that participate in a wide range of cellular processes, however, it lacks the typical features of a signalling receptor. In the TGN, furin mediates the activation of the mature binding form. The encoded protein consists of a large luminal domain, a single transmembrane segment and short C-terminal cytoplasmic tail. The luminal domain contains a cysteine-rich region similar to two corresponding segments in the yeast Vps10p, the cytoplasmic tail is similar to the corresponding segment of the cation-independent mannose 6-phosphate receptor and the tail also interacts with the VHS domains of GGA (Golgi-associated, gamma-adaptin homologous, ARF-interacting) proteins.
Alias Symbols: Gp95, NT3
Protein Interaction Partner: NGFR,SLC2A4,BDNF,GGA1,GGA2,LRPAP1,NGF,NGFR,NTS,CDK2,GGA1,GGA2,LRPAP1,NGF
Protein Size: 831 -
分子量
- 84 kDa
-
基因ID
- 6272
-
NCBI登录号
- NM_002959, NP_002950
-
UniProt
- Q99523
抗原
-
You are here:
