Sorbitol Dehydrogenase (SORD) (N-Term) Peptide
SORD
适用: 人
宿主: 合成
BP, WB
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- 抗原 See all SORD products
- SORD (Sorbitol Dehydrogenase (SORD))
- 蛋白结构域
- N-Term
- 宿主
- 人
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资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB)
- 序列
- ASGTVEKVGS SVKHLKPGDR VAIEPGAPRE NDEFCKMGRY NLSPSIFFCA
- 产品特性
- This is a synthetic peptide designed for use in combination with anti-SORD Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- 纯化方法
- Purified
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- 应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 浓度
- 1 mg/mL
- 缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- 抗原
- SORD (Sorbitol Dehydrogenase (SORD))
- 背景
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Sorbitol dehydrogenase (SORD, EC 1.1.1.14) catalyzes the interconversion of polyols and their corresponding ketoses, and together with aldose reductase (ALDR1, MIM 103880), makes up the sorbitol pathway that is believed to play an important role in the development of diabetic complications (summarized by Carr and Markham, 1995 [PubMed 8535074]). The first reaction of the pathway (also called the polyol pathway) is the reduction of glucose to sorbitol by ALDR1 with NADPH as the cofactor. SORD then oxidizes the sorbitol to fructose using NAD(+) cofactor.
Alias Symbols: SORD1
Protein Interaction Partner: SHBG,SORD,SORD
Protein Size: 357 - 分子量
- 38 kDa
- 基因ID
- 6652
- NCBI登录号
- NM_003104, NP_003095
- UniProt
- Q00796
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