Suppressor of Cytokine Signaling 1 (SOCS1) Peptide
SOCS1
适用: 人
宿主: 合成
BP, WB, IHC
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- 抗原 See all SOCS1 products
- SOCS1 (Suppressor of Cytokine Signaling 1 (SOCS1))
- 宿主
- 人
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资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- 产品特性
- This is a synthetic peptide designed for use in combination with anti-SOCS1 antibody (Catalog #: ARP42147_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- 纯化方法
- Purified
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Suppressor of Cytokine Signaling 1 (SOCS1) peptide
SOCS1 适用: 人, Cow, 小鼠, 大鼠, 犬 宿主: 合成 BP, Imm
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- 应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 浓度
- 1 mg/mL
- 缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- 抗原
- SOCS1 (Suppressor of Cytokine Signaling 1 (SOCS1))
- 别名
- socs1 Peptide, zgc:91868 Peptide, jab Peptide, cis1 Peptide, ssi1 Peptide, tip3 Peptide, cish1 Peptide, ssi-1 Peptide, socs-1 Peptide, SOCS1 Peptide, LOC100228306 Peptide, socs1b Peptide, CIS1 Peptide, CISH1 Peptide, JAB Peptide, SOCS-1 Peptide, SSI-1 Peptide, SSI1 Peptide, TIP3 Peptide, Cish1 Peptide, Cish7 Peptide, Socs-1 Peptide, suppressor of cytokine signaling 1a Peptide, suppressor of cytokine signaling 1 Peptide, suppressor of cytokine signaling 1 L homeolog Peptide, socs1a Peptide, socs1 Peptide, SOCS1 Peptide, socs1.L Peptide, Socs1 Peptide
- 背景
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SOCS1 is a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. SOCS1 functions downstream of cytokine receptors, and takes part in a negative feedback loop to attenuate cytokine signaling. Knockout studies in mice suggested the role of its gene as a modulator of IFN-gamma action, which is required for normal postnatal growth and survival.This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including IL2, IL3 erythropoietin (EPO), CSF2/GM-CSF, and interferon (IFN)-gamma. The protein encoded by this gene functions downstream of cytokine receptors, and takes part in a negative feedback loop to attenuate cytokine signaling. Knockout studies in mice suggested the role of this gene as a modulator of IFN-gamma action, which is required for normal postnatal growth and survival.
Alias Symbols: CIS1, CISH1, JAB, SOCS-1, SSI-1, SSI1, TIP3
Protein Interaction Partner: AXL,CSF1R,FLT3,FYN,GRB2,IGF1R,INSR,ITK,KIT,NCK1,PDGFRB,PIK3R2,TEK,VAV1,VAV2,AXL,COMMD1,CSF1,CSF1R,CXCR4,EGFR,FLT3,FYN,GHR,GRB2,IFNGR1,IGF1R,IL2RB,INSR,IRS1,IRS2,ITK,JAK1,JAK2,JAK3,KIT,MPL,NCK1,PDGFRB,PIK3R1,PIK3R2,PIM2,RELA,TCEB1,TCEB2,TEC,TEK,TIRAP,TRIM8,VAV1,VAV2,ALK,COMMD1,CRK,CSF1R,EGFR,FLT3,FYN,GHR,GRB2,IGF1R,IL2RB,IRS1,IRS2,ITK,JAK2,KIT,MPL,NCK1,RELA,SOCS2,TCEB1,TCEB3,TEC,UBC,VAV1,VAV2
Protein Size: 211 - 分子量
- 23 kDa
- 基因ID
- 8651
- NCBI登录号
- NM_003745, NP_003736
- UniProt
- O15524
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