Small Nuclear Ribonucleoprotein Polypeptides B and B1 (SNRPB) (Middle Region) Peptide
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Quick Overview for Small Nuclear Ribonucleoprotein Polypeptides B and B1 (SNRPB) (Middle Region) Peptide (ABIN984197)
抗原
宿主
资源
应用范围
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蛋白结构域
- Middle Region
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产品特性
- This is a synthetic peptide designed for use in combination with anti-SNRPB antibody (Catalog #: ARP40443_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- SNRPB (Small Nuclear Ribonucleoprotein Polypeptides B and B1 (SNRPB))
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背景
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SNRPB is one of several nuclear proteins that are found in common among U1, U2, U4/U6, and U5 small ribonucleoprotein particles (snRNPs). These snRNPs are involved in pre-mRNA splicing, and the encoded protein may also play a role in pre-mRNA splicing or snRNP structure. Autoantibodies from patients with systemic lupus erythematosus frequently recognize epitopes on the encoded protein. The protein encoded by this gene is one of several nuclear proteins that are found in common among U1, U2, U4/U6, and U5 small ribonucleoprotein particles (snRNPs). These snRNPs are involved in pre-mRNA splicing, and the encoded protein may also play a role in pre-mRNA splicing or snRNP structure. Autoantibodies from patients with systemic lupus erythematosus frequently recognize epitopes on the encoded protein. Two transcript variants encoding different isoforms (B and B') have been found for this gene.
Alias Symbols: COD, SNRPB1, SmB/SmB', snRNP-B, SmB/B', Sm-B/B'
Protein Interaction Partner: GEMIN6,RBBP6,SMN1,ASCC2,C14orf1,CD2BP2,CLNS1A,COIL,CTDP1,DDX20,DHX9,GEMIN4,GEMIN5,GEMIN6,GEMIN7,GIGYF2,LSM11,PRMT5,PSMA3,SKIV2L,SMN2,SMN2,SMNDC1,SNRPB,SNRPD1,SNRPD3,STRAP,STXBP2,STXBP3,TOP3B,WBP4,WDR77,AIRE,ASCC2,C14orf1,CLNS1A,COIL,DDX20,DYNC1H1,EFTUD2,FNBP4,GEMIN4,GEMIN6,GEMIN7,HTATSF1,KHK,LGALS1,MEPCE,PRPF8,PSMA3,SART3,SF3A2,SMN1,SMN2,SNRNP200,SNRPD3,SNUPN,TOP3B,WBP4,WDR77
Protein Size: 231 -
分子量
- 24 kDa
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基因ID
- 6628
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NCBI登录号
- NM_003091, NP_003082
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UniProt
- Q66K91
抗原
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