Small Nuclear Ribonucleoprotein 200kDa (U5) (SNRNP200) (N-Term) Peptide
SNRNP200
适用: 人
宿主: 合成
BP, WB
产品编号 ABIN984189
发货至:
中国
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Contact Info
Our Local Distributor
中国
北京 101111
北京 101111
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Quick Overview for Small Nuclear Ribonucleoprotein 200kDa (U5) (SNRNP200) (N-Term) Peptide (ABIN984189)
抗原
SNRNP200
(Small Nuclear Ribonucleoprotein 200kDa (U5) (SNRNP200))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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蛋白结构域
- N-Term
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序列
- GDEDVYGEVR EEASDDDMEG DEAVVRCTLS ANLVASGELM SSKKKDLHPR
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产品特性
- This is a synthetic peptide designed for use in combination with anti-SNRNP200 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- SNRNP200 (Small Nuclear Ribonucleoprotein 200kDa (U5) (SNRNP200))
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背景
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Pre-mRNA splicing is catalyzed by the spliceosome, a complex of specialized RNA and protein subunits that removes introns from a transcribed pre-mRNA segment. The spliceosome consists of small nuclear RNA proteins (snRNPs) U1, U2, U4, U5 and U6, together with approximately 80 conserved proteins. U5 snRNP contains nine specific proteins. This gene encodes one of the U5 snRNP-specific proteins. This protein belongs to the DEXH-box family of putative RNA helicases. It is a core component of U4/U6-U5 snRNPs and appears to catalyze an ATP-dependent unwinding of U4/U6 RNA duplices. Mutations in this gene cause autosomal-dominant retinitis pigmentosa.
Alias Symbols: ASCC3L1, BRR2, FLJ11521, HELIC2, RP33, U5-200KD
Protein Interaction Partner: CHMP1B,MEGF10,SMNDC1,YWHAB,YWHAG,APC,CD2BP2,MCC,MEPCE,MYC,PIN1,PRKAB1,RNPS1,RNU11,RNU12-2P,SMNDC1,SNRNP40,SNRPB,SRRM1,TCEA1,USP39,YWHAG,tat
Protein Size: 2136 -
分子量
- 244 kDa
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基因ID
- 23020
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NCBI登录号
- NM_014014, NP_054733
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UniProt
- O75643
抗原
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