Serine/threonine-Protein Phosphatase 4 Regulatory Subunit 3A (SMEK1) (Middle Region) Peptide
SMEK1
适用: 人
宿主: 合成
BP, WB
产品编号 ABIN984129
发货至:
中国
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Contact Info
Our Local Distributor
中国
北京 101111
北京 101111
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Quick Overview for Serine/threonine-Protein Phosphatase 4 Regulatory Subunit 3A (SMEK1) (Middle Region) Peptide (ABIN984129)
抗原
SMEK1
(Serine/threonine-Protein Phosphatase 4 Regulatory Subunit 3A (SMEK1))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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蛋白结构域
- Middle Region
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序列
- YWKALEDVDY VQTFKGLKLR FEQQRERQDN PKLDSMRSIL RNHRYRRDAR
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产品特性
- This is a synthetic peptide designed for use in combination with anti-SMEK1 Antibody(ARP57688_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- SMEK1 (Serine/threonine-Protein Phosphatase 4 Regulatory Subunit 3A (SMEK1))
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背景
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SMEK1 is the regulatory subunit of serine/threonine-protein phosphatase 4.SMEK1 may regulate the activity of PPP4C at centrosomal microtubule organizing centers. The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AFX phosphorylated on 'Ser-140' (gamma-H2AFX) generated during DNA replication and required for DNA DSB repair.
Alias Symbols: FLFL1, KIAA2010, MSTP033, smk-1, smk1, PP4R3A
Protein Interaction Partner: MAPK14,PPP4C,PPP4R2
Protein Size: 820 -
分子量
- 94 kDa
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基因ID
- 55671
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NCBI登录号
- NM_032560, NP_115949
抗原
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