Sialic Acid Binding Ig-Like Lectin 7 (SIGLEC7) (Middle Region) Peptide
SIGLEC7
适用: 人
宿主: 合成
WB, BP
产品编号 ABIN983742
发货至:
中国
Contact our Customer Service for availability and price in your country.
Contact Info
Our Local Distributor
中国
北京 101111
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
Quick Overview for Sialic Acid Binding Ig-Like Lectin 7 (SIGLEC7) (Middle Region) Peptide (ABIN983742)
抗原
SIGLEC7
(Sialic Acid Binding Ig-Like Lectin 7 (SIGLEC7))
宿主
人
资源
合成
应用范围
Western Blotting (WB), Blocking Peptide (BP)
-
-
蛋白结构域
- Middle Region
-
产品特性
- This is a synthetic peptide designed for use in combination with anti-SIGLEC7 antibody (Catalog #: ARP47017_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
-
纯化方法
- Purified
-
-
-
-
应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
-
浓度
- 1 mg/mL
-
缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
-
注意事项
- Avoid repeated freeze-thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
-
- SIGLEC7 (Sialic Acid Binding Ig-Like Lectin 7 (SIGLEC7))
-
背景
-
SIGLEC7 is a putative adhesion molecule that mediates sialic-acid dependent binding to cells. In the immune response, it may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. SIGLEC7 mediates inhibition of natural killer cells cytotoxicity. It may also play a role in hemopoiesis. SIGLEC7 inhibits differentiation of CD34+ cell precursors towards myelomonocytic cell lineage and proliferation of leukemic myeloid cells (in vitro).
Alias Symbols: AIRM1, CDw328, D-siglec, QA79, SIGLEC-7, p75, p75/AIRM1, CD328
Protein Interaction Partner: GRB2,PTPN11,TRAF4
Protein Size: 467 -
分子量
- 51 kDa
-
基因ID
- 27036
-
NCBI登录号
- NM_014385, NP_055200
-
UniProt
- Q9Y286
抗原
-
You are here:
