Stratifin (SFN) (Middle Region) Peptide
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Quick Overview for Stratifin (SFN) (Middle Region) Peptide (ABIN983633)
抗原
宿主
资源
应用范围
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蛋白结构域
- Middle Region
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产品特性
- This is a synthetic peptide designed for use in combination with anti-SFN antibody (Catalog #: ARP54792_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- 14-3-3 sigma/SFN (SFN) (Stratifin (SFN))
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背景
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SFN is an adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathway. SFN binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, SFN regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway.
Alias Symbols: YWHAS
Protein Interaction Partner: TP53,TP53,ABL1,BAD,BAX,BCR,CCAR1,CDC25B,CDK1,CHST1,EEF1A1,EGFR,EIF2S1,EIF4B,FAM189A2,GPRIN2,HDAC5,HNRNPD,ING1,KCNK15,KCNK3,KCNK9,KIAA0408,MAP3K5,MARK3,MDM4,MST1R,NR3C1,PLEKHF2,PLK4,TBL3,TRIM25,TSC2,WDYHV1,YWHAG,ZFP36,ABLIM1,ANKS1A,APC,APLP2,ARAF,ARHGAP11A,ARHGAP21,ARHGAP32,ARHGEF16,ARHGEF17,ARHGEF5,BAD,BCAR1,BRAF,CDK1,CGN,CHEK1,CHST1,CSNK2A1,CYTH2,DCAF7,DTX2,DYRK1A,ERRFI1,FAM189A2,GAN,GPRIN2,GRB7,HDAC4,HDAC7,HNRNPU,IRS1,IRS2,ISCU,ITCH,JUB,KIAA0408,KIF23,KIF5B,KLC1,KLC2,KLHDC2,LAD1,LMO7,LSR,MAGI1,MAP3K2,MAPKAP1,MARK1,MARK2,MARK3,MDM2,MPRIP,MYCBP2,NEDD4L,NR3C1,OSBPL3,PAK4,PARD3,PARD3B,PI4KB,PIK3C2B,PKP2,PKP3,PLEKHF2,PLK4,PPFIBP1,PPFIBP2,PPP1R3D,PTOV1,PTPN2,PTPN3,RACGAP1,RAE1,RAF1,RALGPS2,RHPN2,RND3,SASH1,SAV1,SH2D3A,SH3BP4,SHCBP1,SHROOM3,SIPA1L1,SIPA1L3,SORBS2,SPIRE1,SRRM2,SRSF10,ST5,SYNJ2,TBL3,TJP2,TNK1,TNS4,TP53,TRIM25,TRIM32,UBC,USP8,WDYHV1,WEE1,YWHAG,ZAK,ZNF638
Protein Size: 248 -
分子量
- 28 kDa
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基因ID
- 2810
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NCBI登录号
- NM_006142, NP_006133
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UniProt
- P31947
抗原
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