Splicing Factor 3b, Subunit 4, 49kDa (SF3B4) Peptide
SF3B4
适用: 人
宿主: 合成
BP, WB
Quick Overview for Splicing Factor 3b, Subunit 4, 49kDa (SF3B4) Peptide (ABIN983628)
抗原
SF3B4
(Splicing Factor 3b, Subunit 4, 49kDa (SF3B4))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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产品特性
- This is a synthetic peptide designed for use in combination with anti-SF3B4 antibody (Catalog #: ARP40610_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- SF3B4 (Splicing Factor 3b, Subunit 4, 49kDa (SF3B4))
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背景
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SF3B4 is one of four subunits of the splicing factor 3B. The protein cross-links to a region in the pre-mRNA immediately upstream of the branchpoint sequence in pre-mRNA in the prespliceosomal complex A. It also may be involved in the assembly of the B, C and E spliceosomal complexes. In addition to RNA-binding activity, this protein interacts directly and highly specifically with subunit 2 of the splicing factor 3B. This protein contains two N-terminal RNA-recognition motifs (RRMs), consistent with the observation that it binds directly to pre-mRNA.This gene encodes one of four subunits of the splicing factor 3B. The protein encoded by this gene cross-links to a region in the pre-mRNA immediately upstream of the branchpoint sequence in pre-mRNA in the prespliceosomal complex A. It also may be involved in the assembly of the B, C and E spliceosomal complexes. In addition to RNA-binding activity, this protein interacts directly and highly specifically with subunit 2 of the splicing factor 3B. This protein contains two N-terminal RNA-recognition motifs (RRMs), consistent with the observation that it binds directly to pre-mRNA.This gene encodes one of four subunits of the splicing factor 3B. The protein encoded by this gene cross-links to a region in the pre-mRNA immediately upstream of the branchpoint sequence in pre-mRNA in the prespliceosomal complex A. It also may be involved in the assembly of the B, C and E spliceosomal complexes. In addition to RNA-binding activity, this protein interacts directly and highly specifically with subunit 2 of the splicing factor 3B. This protein contains two N-terminal RNA-recognition motifs (RRMs), consistent with the observation that it binds directly to pre-mRNA.
Alias Symbols: AFD1, Hsh49, SAP49, SF3b49
Protein Interaction Partner: SF3B2,BMPR1A,FAM115A,MAPK9,NCK2,SF3B2,SS18L1,STK19,SUMO4,TCERG1,BMPR1A,CDC5L,FAM115A,MAPK9,NCK2,RNU11,RNU12-2P,SF3A2,SF3B1,SF3B2,SMNDC1,SS18L1,TCERG1
Protein Size: 424 -
分子量
- 47 kDa
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基因ID
- 10262
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NCBI登录号
- NM_005850, NP_005841
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UniProt
- Q15427
抗原
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