Retinoid X Receptor, gamma (RXRG) Peptide
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Quick Overview for Retinoid X Receptor, gamma (RXRG) Peptide (ABIN983357)
抗原
宿主
资源
应用范围
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产品特性
- This is a synthetic peptide designed for use in combination with anti-RXRG antibody (Catalog #: ARP38881_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Retinoid X Receptor gamma (RXRG) (Retinoid X Receptor, gamma (RXRG))
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背景
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RXRG encodes a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating the antiproliferative effects of retinoic acid (RA). This receptor forms dimers with the retinoic acid, thyroid hormone, and vitamin D receptors, increasing both DNA binding and transcriptional function on their respective response elements. RXRG is expressed at significantly lower levels in non-small cell lung cancer cells. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.This gene encodes a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating the antiproliferative effects of retinoic acid (RA). This receptor forms dimers with the retinoic acid, thyroid hormone, and vitamin D receptors, increasing both DNA binding and transcriptional function on their respective response elements. This gene is expressed at significantly lower levels in non-small cell lung cancer cells. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Alias Symbols: NR2B3, RXRC
Protein Interaction Partner: CAMK2B,CHGB,CREBBP,LRSAM1,MAP4,NCOA6,NCOR2,NR1H2,NR1H3,NR1H4,NR1I2,NR4A1,PNO1,PPARA,PPARD,PPARG,RARA,RARB,RARG,SRF,THRA,THRB,VDR,ITGB3BP,JUB,NR0B2,NR4A1,Nr0b2,PPARA,RARA,RPAP2,SRF
Protein Size: 463 -
分子量
- 51 kDa
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基因ID
- 6258
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NCBI登录号
- NM_006917, NP_008848
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UniProt
- P48443
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