Runt-Related Transcription Factor 2 (RUNX2) Peptide
RUNX2
宿主: 合成
BP, WB
产品编号 ABIN983331
发货至:
中国
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Contact Info
Our Local Distributor
中国
北京 101111
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
Quick Overview for Runt-Related Transcription Factor 2 (RUNX2) Peptide (ABIN983331)
抗原
RUNX2
(Runt-Related Transcription Factor 2 (RUNX2))
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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产品特性
- This is a synthetic peptide designed for use in combination with anti-RUNX2 antibody (Catalog #: ARP36679_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- RUNX2 (Runt-Related Transcription Factor 2 (RUNX2))
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背景
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The RUNX2 gene is a member of the RUNX family of transcription factors and encodes a nuclear protein with an Runt DNA-binding domain. This protein is essential for osteoblastic differentiation and skeletal morphogenesis, acting as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. The protein can bind DNA both as a monomer or, with more affinity, as a subunit of a heterodimeric complex. Mutations in this gene have been associated with the bone development disorder cleidocranial dysplasia (CCD).
Protein Interaction Partner: RB1,AR,AXIN1,CBFB,CCNB1,CDK1,CEBPB,DVL2,EP300,ETS1,FOS,HDAC3,HDAC4,HDAC6,JUN,LEF1,MAP3K4,MSX2,MYST4,PRKCD,RB1,SMAD2,SMAD3,SMAD6,TAF1A,UBTF,XRCC5,XRCC6,YAP1,ETS1,FOS,HDAC3,HDAC4,HDAC6,JUN,LEF1,MSX2,MYST4,SMAD1,SMAD2,SMAD3,SMAD5,STUB1,THOC4,TLE1,YAP1
Protein Size: 589 -
分子量
- 64 kDa
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基因ID
- 860
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UniProt
- Q5T802
抗原
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