Runt-Related Transcription Factor 1 (RUNX1) Peptide
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Quick Overview for Runt-Related Transcription Factor 1 (RUNX1) Peptide (ABIN983324)
抗原
宿主
资源
应用范围
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产品特性
- This is a synthetic peptide designed for use in combination with anti-RUNX1 antibody (Catalog #: ARP38073_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- RUNX1 (Runt-Related Transcription Factor 1 (RUNX1))
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背景
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Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. RUNX1 is the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with severaltypes of leukemia.
Alias Symbols: AML1, CBFA2, EVI-1, AMLCR1, PEBP2aB, AML1-EVI-1
Protein Interaction Partner: CBFB,TLE1,CBFB,TLE1,AR,CBFA2T2,CBFA2T3,CBFB,CCND1,CCND2,CCND3,CDK6,CEBPA,CEBPB,ELF2,ELF4,EP300,FOS,FOXP3,HIPK1,HIPK2,JUN,MYST3,MYST4,NCOR2,PAX5,SUV39H1,TLE1,TLE2,WWTR1,YAP1,AES,CBFA2T2,CBFB,CEBPB,EFNA2,ELF2,ELF4,ETS1,FHL2,FOS,JUN,LEF1,MYOD1,MYST4,PAX5,SMAD1,SMAD2,SMAD3,SMAD5,SUV39H1,TLE1,TRAF6,VDR,YAP1
Protein Size: 107 -
分子量
- 12 kDa
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基因ID
- 861
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NCBI登录号
- NM_001001890
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UniProt
- Q01196
抗原
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