This is a synthetic peptide designed for use in combination with anti-RTN4 antibody (Catalog #: ARP46812_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
RTN4 belongs to the family of reticulons. Reticulons are associated with the endoplasmic reticulum, and are involved in neuroendocrine secretion or in membrane trafficking in neuroendocrine cells. RTN4 is a potent neurite outgrowth inhibitor which may also help block the regeneration of the central nervous system in higher vertebrates.This gene belongs to the family of reticulon encoding genes. Reticulons are associated with the endoplasmic reticulum, and are involved in neuroendocrine secretion or in membrane trafficking in neuroendocrine cells. The product of this gene is a potent neurite outgrowth inhibitor which may also help block the regeneration of the central nervous system in higher vertebrates. Alternatively spliced transcript variants derived both from differential splicing and differential promoter usage and encoding different isoforms have been identified.This gene belongs to the family of reticulon encoding genes. Reticulons are associated with the endoplasmic reticulum, and are involved in neuroendocrine secretion or in membrane trafficking in neuroendocrine cells. The product of this gene is a potent neurite outgrowth inhibitor which may also help block the regeneration of the central nervous system in higher vertebrates. Alternatively spliced transcript variants derived both from differential splicing and differential promoter usage and encoding different isoforms have been identified.
Protein Interaction Partner: RTN4IP1,UQCRC1,UQCRC2,BCL2,BCL2L1,BCL2,BCL2L1,CNTNAP1,COL4A3BP,CRMP1,FXR2,LRCH4,LRPAP1,MBP,NAPA,PLEKHF2,PRR13,RAB33A,RTN3,RTN4IP1,RTN4R,SPG21,TUBA4A,UQCRC1,UQCRC2,BCL2,BCL2L1,CNTNAP1,COL4A3BP,CRMP1,FXR2,KCNA1,KCNA2,LRCH4,LRPAP1,NAPA,PLEKHF2,PRR13,RAB33A,RTN3,RTN4IP1,RTN4R,SIRT2,SPG21,UQCRC1,UQCRC2,WWP1