RNA-Binding Region (RNP1, RRM) Containing 3 (RNPC3) (Middle Region) Peptide
RNPC3
适用: 人
宿主: 合成
BP, WB
Quick Overview for RNA-Binding Region (RNP1, RRM) Containing 3 (RNPC3) (Middle Region) Peptide (ABIN983111)
抗原
RNP (RNPC3)
(RNA-Binding Region (RNP1, RRM) Containing 3 (RNPC3))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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蛋白结构域
- Middle Region
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产品特性
- This is a synthetic peptide designed for use in combination with anti-RNPC3 antibody (Catalog #: ARP40868_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- RNP (RNPC3) (RNA-Binding Region (RNP1, RRM) Containing 3 (RNPC3))
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背景
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RNPC3 is an RNA-binding protein involved in pre-mRNA splicing. RNPC3 participates in pre-mRNA U12-dependent splicing. RNPC3 binds to the 3'-stem-loop of m7G-capped U12 snRNA.Two types of spliceosomes catalyze splicing of pre-mRNAs. The major U2-type spliceosome is found in all eukaryotes and removes U2-type introns, which represent more than 99 % of pre-mRNA introns. The minor U12-type spliceosome is found in some eukaryotes and removes U12-type introns, which are rare and have distinct splice consensus signals. The U12-type spliceosome consists of several small nuclear RNAs and associated proteins. This gene encodes a 65K protein that is a component of the U12-type spliceosome. This protein contains two RNA recognition motifs (RRMs), suggesting that it may contact one of the small nuclear RNAs of the minor spliceosome.
Alias Symbols: FLJ20008, FLJ25070, KIAA183, RBM40, RNP
Protein Interaction Partner: RNU11,RNU12-2P
Protein Size: 517 -
分子量
- 58 kDa
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基因ID
- 55599
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NCBI登录号
- NM_017619, NP_060089
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UniProt
- Q96LT9
抗原
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