Renalase, FAD-Dependent Amine Oxidase (RNLS) (Middle Region) Peptide
RNLS
适用: 人, 小鼠
宿主: 合成
BP, WB
Quick Overview for Renalase, FAD-Dependent Amine Oxidase (RNLS) (Middle Region) Peptide (ABIN983108)
抗原
RNLS
(Renalase, FAD-Dependent Amine Oxidase (RNLS))
宿主
人, 小鼠
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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蛋白结构域
- Middle Region
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序列
- GMKIGVPWSC RYLSSHPCIC FISIDNKKRN IESSECGPSV VIQTTVPFGV
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产品特性
- This is a synthetic peptide designed for use in combination with anti-Rnls Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- RNLS (Renalase, FAD-Dependent Amine Oxidase (RNLS))
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背景
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Rnls is a probable FAD-dependent amine oxidase secreted by the kidney, which circulates in blood and modulates cardiac function and systemic blood pressure. It degrades catecholamines such as dopamine, norepinephrine and epinephrine in vitro. It lowers blood pressure in vivo by decreasing cardiac contractility and heart rate and preventing a compensatory increase in peripheral vascular tone, suggesting a causal link to the increased plasma catecholamine and heightened cardiovascular risk. High concentrations of catecholamines activate plasma renalase and promotes its secretion and synthesis.
Alias Symbols: 6530404N21Rik, AI452315, AW060440, C10orf59
Protein Size: 300 -
分子量
- 33 kDa
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基因ID
- 67795
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NCBI登录号
- NM_001167818, NP_001161290
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UniProt
- A7RDN6
抗原
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