Receptor-Interacting serine-threonine Kinase 3 (RIPK3) Peptide
RIPK3
适用: 人
宿主: 合成
BP, WB, IHC
Quick Overview for Receptor-Interacting serine-threonine Kinase 3 (RIPK3) Peptide (ABIN983003)
抗原
RIPK3
(Receptor-Interacting serine-threonine Kinase 3 (RIPK3))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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产品特性
- This is a synthetic peptide designed for use in combination with anti-RIPK3 antibody (Catalog #: ARP31513_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- RIPK3 (Receptor-Interacting serine-threonine Kinase 3 (RIPK3))
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背景
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RIPK3 is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, and contains a C-terminal domain unique from other RIP family members. The protein is predominantly localized to the cytoplasm, and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor.The product of this gene is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, and contains a C-terminal domain unique from other RIP family members. The encoded protein is predominantly localized to the cytoplasm, and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor.
Alias Symbols: RIP3, RIP3 beta, RIP3 gamma
Protein Interaction Partner: RIPK1,TICAM1,TNFRSF1A,TRAF2,RIPK1,TICAM1,TNFRSF1A,TRAF2
Protein Size: 518 -
分子量
- 57 kDa
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基因ID
- 11035
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NCBI登录号
- NM_006871, NP_006862
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UniProt
- Q9Y572
抗原
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