Ring Finger Protein 1 (RING1) (Middle Region) Peptide
RING1
适用: 人
宿主: 合成
BP, WB
产品编号 ABIN982993
发货至:
中国
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Quick Overview for Ring Finger Protein 1 (RING1) (Middle Region) Peptide (ABIN982993)
抗原
RING1
(Ring Finger Protein 1 (RING1))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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蛋白结构域
- Middle Region
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产品特性
- This is a synthetic peptide designed for use in combination with anti-RING1 antibody (Catalog #: ARP33228_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- RING1 (Ring Finger Protein 1 (RING1))
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背景
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RING1 belongs to the RING finger family, members of which characterized by a RING domain, a zinc-binding motif related to the zinc finger domain. The protein can bind DNA and can act as a transcriptional repressor. It is associated with the multimeric polycomb group protein complex. RING1 interacts with the polycomb group proteins BMI1, EDR1, and CBX4, and colocalizes with these proteins in large nuclear domains. It interacts with the CBX4 protein via its glycine-rich C-terminal domain. This gene maps to the HLA class II region, where it is contiguous with the RING finger genes FABGL and HKE4.This gene belongs to the RING finger family, members of which encode proteins characterized by a RING domain, a zinc-binding motif related to the zinc finger domain. The gene product can bind DNA and can act as a transcriptional repressor. It is associated with the multimeric polycomb group protein complex. The gene product interacts with the polycomb group proteins BMI1, EDR1, and CBX4, and colocalizes with these proteins in large nuclear domains. It interacts with the CBX4 protein via its glycine-rich C-terminal domain. The gene maps to the HLA class II region, where it is contiguous with the RING finger genes FABGL and HKE4. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: RNF1, RING1A
Protein Interaction Partner: BMI1,CBX4,RING1,FHL1,BMI1,CBX4,CBX7,CBX8,E2F6,ELAC2,FHL1,PHC1,RB1,RING1,RNF2,RYBP,BCOR,BMI1,Bmi1,CBX2,CBX3,CBX4,CBX7,CBX8,Cbx2,E2F1,E2F6,KDM5C,PCGF1,PCGF2,PHC1,RB1,RING1,RNF2,RYBP,cbx2
Protein Size: 406 -
分子量
- 42 kDa
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基因ID
- 6015
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NCBI登录号
- NM_002931, NP_002922
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UniProt
- Q06587
抗原
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