Ras Homolog Gene Family, Member B (RHOB) (Middle Region) Peptide
RHOB
适用: 人
宿主: 合成
BP, WB
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- 抗原 See all RHOB products
- RHOB (Ras Homolog Gene Family, Member B (RHOB))
- 蛋白结构域
- Middle Region
- 宿主
- 人
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资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB)
- 序列
- CPNVPIILVA NKKDLRSDEH VRTELARMKQ EPVRTDDGRA MAVRIQAYDY
- 产品特性
- This is a synthetic peptide designed for use in combination with anti-RHOB Antibody(ARP54702_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- 纯化方法
- Purified
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- 应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 浓度
- 1 mg/mL
- 缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- 抗原
- RHOB (Ras Homolog Gene Family, Member B (RHOB))
- 背景
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RHOB mediates apoptosis in neoplastically transformed cells after DNA damage.RHOB is not essential for development but affects cell adhesion and growth factor signaling in transformed cells.RHOB plays a negative role in tumorigenesis as deletion causes tumor formation. RHOB is involved in intracellular protein trafficking of a number of proteins.RHOB targets PKN1 to endosomes and is involved in trafficking of the EGF receptor from late endosomes to lysosomes.RHOB is also required for stability and nuclear trafficking of AKT1/AKT which promotes endothelial cell survival during vascular development.
Alias Symbols: ARH6, ARHB, MST081, MSTP081, RHOH6
Protein Interaction Partner: ARHGDIG,ARHGEF3,FNTA,PDE6D,PGGT1B,PPP2CA,RHPN2,ARHGDIG,ARHGEF3,CIT,PDE6D,RHPN2
Protein Size: 196 - 分子量
- 22 kDa
- 基因ID
- 388
- NCBI登录号
- NM_004040, NP_004031
- UniProt
- P62745
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