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RE1-Silencing Transcription Factor (REST) (Middle Region) Peptide

REST 适用: 人 宿主: 合成 BP, WB
产品编号 ABIN982856
发货至: 中国
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Quick Overview for RE1-Silencing Transcription Factor (REST) (Middle Region) Peptide (ABIN982856)

抗原

REST (RE1-Silencing Transcription Factor (REST))

宿主

资源

  • 6
合成

应用范围

Blocking Peptide (BP), Western Blotting (WB)
  • 蛋白结构域

    Middle Region

    产品特性

    This is a synthetic peptide designed for use in combination with anti-REST antibody (Catalog #: ARP32478_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    纯化方法

    Purified
  • 应用备注

    Each Investigator should determine their own optimal working dilution for specific applications.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    浓度

    1 mg/mL

    缓冲液

    Final peptide concentration is 1 mg/mL in PBS.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原

    REST (RE1-Silencing Transcription Factor (REST))

    背景

    REST is a transcriptional repressor which represses neuronal genes in non-neuronal tissues. It is a member of the Kruppel-type zinc finger transcription factor family. It represses transcription by binding a DNA sequence element called the neuron-restrictive silencer element. The protein is also found in undifferentiated neuronal progenitor cells, and it is thought that this repressor may act as a master negative regular of neurogenesis.This gene encodes a transcriptional repressor which represses neuronal genes in non-neuronal tissues. It is a member of the Kruppel-type zinc finger transcription factor family. It represses transcription by binding a DNA sequence element called the neuron-restrictive silencer element. The protein is also found in undifferentiated neuronal progenitor cells, and it is thought that this repressor may act as a master negative regular of neurogenesis. Alternatively spliced transcript variants have been described, however, their full length nature has not been determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

    Alias Symbols: NRSF, XBR

    Protein Interaction Partner: CTDSP1,EHMT2,GRM2,STMN2,HTT,RCOR1,SIN3B,HDAC1,HDAC2,Hdac1,KDM5C,NCOR1,RCOR1,RNF2,Sin3a,Sin3b

    Protein Size: 1097

    分子量

    122 kDa

    基因ID

    5978

    NCBI登录号

    NM_005612, NP_005603

    UniProt

    Q13127
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