Retinol Dehydrogenase 12 (All-Trans/9-Cis/11-Cis) (RDH12) (Middle Region) Peptide
RDH12
适用: 人
宿主: 合成
BP, WB
产品编号 ABIN982813
发货至:
中国
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Contact Info
Our Local Distributor
中国
北京 101111
北京 101111
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Quick Overview for Retinol Dehydrogenase 12 (All-Trans/9-Cis/11-Cis) (RDH12) (Middle Region) Peptide (ABIN982813)
抗原
RDH12
(Retinol Dehydrogenase 12 (All-Trans/9-Cis/11-Cis) (RDH12))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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蛋白结构域
- Middle Region
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产品特性
- This is a synthetic peptide designed for use in combination with anti-RDH12 antibody (Catalog #: ARP52972_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- RDH12 (Retinol Dehydrogenase 12 (All-Trans/9-Cis/11-Cis) (RDH12))
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背景
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RDH12 is an NADPH-dependent retinal reductase whose highest activity is toward 9-cis and all-trans-retinol. RDH12 also plays a role in the metabolism of short-chain aldehydes but does not exhibit steroid dehydrogenase activity. Defects in this gene are a cause of Leber congenital amaurosis type 3 (LCA3).The protein encoded by this gene is an NADPH-dependent retinal reductase whose highest activity is toward 9-cis and all-trans-retinol. The encoded enzyme also plays a role in the metabolism of short-chain aldehydes but does not exhibit steroid dehydrogenase activity. Defects in this gene are a cause of Leber congenital amaurosis type 3 (LCA3).
Alias Symbols: FLJ30273, LCA3, LCA13, SDR7C2
Protein Size: 316 -
分子量
- 35 kDa
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基因ID
- 145226
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NCBI登录号
- NM_152443, NP_689656
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UniProt
- Q96NR8
抗原
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