RAS Protein Activator Like 1 (GAP1 Like) (RASAL1) (C-Term) Peptide
RASAL1
适用: 人
宿主: 合成
BP, WB
Quick Overview for RAS Protein Activator Like 1 (GAP1 Like) (RASAL1) (C-Term) Peptide (ABIN982671)
抗原
RASAL1
(RAS Protein Activator Like 1 (GAP1 Like) (RASAL1))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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蛋白结构域
- C-Term
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序列
- DTTLEADTGA CPEVLARQRA ATARLLEVLA DLDRAHEEFQ QQERGKAALG
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产品特性
- This is a synthetic peptide designed for use in combination with anti-RASAL1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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RAS Protein Activator Like 1 (GAP1 Like) (RASAL1) peptide
RASAL1 适用: 人 宿主: 合成 BP, Imm
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- RASAL1 (RAS Protein Activator Like 1 (GAP1 Like) (RASAL1))
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背景
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The protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins. These proteins stimulate the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. This particular family member contains domains which are characteristic of the GAP1 subfamily of RasGAP proteins but, in contrast to the other GAP1 family members, this protein is strongly and selectively expressed in endocrine tissues. Alternatively spliced transcript variants that encode different isoforms have been described.
Alias Symbols: RASAL
Protein Interaction Partner: PITX1
Protein Size: 804 -
分子量
- 88 kDa
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基因ID
- 8437
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NCBI登录号
- NM_004658, NP_004649
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UniProt
- O95294
抗原
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