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Retinoic Acid Receptor, beta (RARB) Peptide

RARB 适用: 人 宿主: 合成 BP, WB, IHC
产品编号 ABIN982664
发货至: 中国
  • 抗原 See all Retinoic Acid Receptor beta (RARB) products
    Retinoic Acid Receptor beta (RARB) (Retinoic Acid Receptor, beta (RARB))
    宿主
    资源
    • 3
    合成
    应用范围
    Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
    产品特性
    This is a synthetic peptide designed for use in combination with anti-RARB antibody (Catalog #: ARP45601_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    纯化方法
    Purified
  • 应用备注
    Each Investigator should determine their own optimal working dilution for specific applications.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    浓度
    1 mg/mL
    缓冲液
    Final peptide concentration is 1 mg/mL in PBS.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原
    Retinoic Acid Receptor beta (RARB) (Retinoic Acid Receptor, beta (RARB))
    别名
    RARB Peptide, nRARs Peptide, HAP Peptide, NR1B2 Peptide, RRB2 Peptide, A830025K23 Peptide, Hap Peptide, Nr1b2 Peptide, RARbeta2 Peptide, RARBETA Peptide, retinoic acid receptor beta Peptide, retinoic acid receptor, beta Peptide, RARB Peptide, Rarb Peptide
    背景
    RARB is a retinoic acid receptor beta, a member of the thyroid-steroid hormone receptor superfamily of nuclear transcriptional regulators. This receptor localizes to the cytoplasm and to subnuclear compartments. It binds retinoic acid, the biologically active form of vitamin A which mediates cellular signalling in embryonic morphogenesis, cell growth and differentiation. It is thought that this protein limits growth of many cell types by regulating gene expression. This gene encodes retinoic acid receptor beta, a member of the thyroid-steroid hormone receptor superfamily of nuclear transcriptional regulators. This receptor localizes to the cytoplasm and to subnuclear compartments. It binds retinoic acid, the biologically active form of vitamin A which mediates cellular signalling in embryonic morphogenesis, cell growth and differentiation. It is thought that this protein limits growth of many cell types by regulating gene expression. The gene was first identified in a hepatocellular carcinoma where it flanks a hepatitis B virus integration site. The gene expresses at least two transcript variants, one additional transcript has been described, but its full length nature has not been determined.

    Alias Symbols: HAP, NR1B2, RRB2

    Protein Interaction Partner: DNMT1,DNMT3A,DNMT3B,HDAC1,HIST4H4,MAP6,NCOA1,NCOA3,NCOR2,PNRC1,RXRA,RXRB,RXRG,SMAD2,CEBPA,CEBPB,NCOA1,NR4A2

    Protein Size: 448
    分子量
    50 kDa
    基因ID
    5915
    NCBI登录号
    NM_000965, NP_000956
    UniProt
    P10826
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