RAE1 RNA Export 1 Homolog (S. Pombe) (RAE1) Peptide
RAE1
适用: 人
宿主: 合成
BP, IHC, WB
产品编号 ABIN982620
发货至:
中国
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Contact Info
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中国
北京 101111
北京 101111
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Quick Overview for RAE1 RNA Export 1 Homolog (S. Pombe) (RAE1) Peptide (ABIN982620)
抗原
RAE1
(RAE1 RNA Export 1 Homolog (S. Pombe) (RAE1))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
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产品特性
- This is a synthetic peptide designed for use in combination with anti-RAE1 antibody (Catalog #: ARP40301_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- RAE1 (RAE1 RNA Export 1 Homolog (S. Pombe) (RAE1))
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背景
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RAE1 is a homolog of yeast Rae1. It contains four WD40 motifs, and has been shown to localize to distinct foci in the nucleoplasm, to the nuclear rim, and to meshwork-like structures throughout the cytoplasm. This gene is thought to be involved in nucleocytoplasmic transport, and in directly or indirectly attaching cytoplasmic mRNPs to the cytoskeleton.Mutations in the Schizosaccharomyces pombe Rae1 and Saccharomyces cerevisiae Gle2 genes have been shown to result in accumulation of poly(A)-containing mRNA in the nucleus, suggesting that the encoded proteins are involved in RNA export. The protein encoded by this gene is a homolog of yeast Rae1. It contains four WD40 motifs, and has been shown to localize to distinct foci in the nucleoplasm, to the nuclear rim, and to meshwork-like structures throughout the cytoplasm. This gene is thought to be involved in nucleocytoplasmic transport, and in directly or indirectly attaching cytoplasmic mRNPs to the cytoskeleton. Alternatively spliced transcript variants encoding the same protein have been found for this gene.
Alias Symbols: MIG14, MRNP41, Mnrp41, dJ481F12.3, dJ800J21.1
Protein Interaction Partner: BUB1,DDX24,KLRC4,NUP98,NXF1,AGGF1,ARMC8,ATE1,BUB1,Bub1,COPS6,COPS8,CS,DDX19B,FAF1,FAM122B,HSP90B1,KLRK1,MAGED4B,MAP1B,MIOS,MPST,MYCBP2,NUP188,NUP214,NUP62,NUP88,NUP93,NUP98,NUPL2,POLA1,POLA2,POLR3A,POLR3B,POLR3E,POLR3H,PRIM1,PRIM2,PRKD2,PRKD3,RBM8A,SART1,SEH1L,SF3A1,SF3A2,SF3A3,SFN,SMC1A,SMC3,SMU1,TJP1,TJP2,UFD1L,USP11,USP7,WDR24,WDR26,WDR59,WDR75
Protein Size: 368 -
分子量
- 40 kDa
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基因ID
- 8480
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NCBI登录号
- NM_001015885, NP_001015885
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UniProt
- P78406
抗原
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