RAD23 Homolog A (RAD23A) Peptide
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Quick Overview for RAD23 Homolog A (RAD23A) Peptide (ABIN982604)
抗原
宿主
资源
应用范围
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产品特性
- This is a synthetic peptide designed for use in combination with anti-RAD23A antibody (Catalog #: ARP42210_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- RAD23A (RAD23 Homolog A (RAD23A))
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背景
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RAD23A is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in nucleotide excision repair (NER). This protein was shown to interact with, and elevate the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), which suggested a role in DNA damage recognition in base excision repair. This protein contains an N-terminal ubiquitin-like domain, which was reported to interact with 26S proteasome, as well as with ubiquitin protein ligase E6AP, and thus suggests that this protein may be involved in the ubiquitin mediated proteolytic pathway in cells.The protein encoded by this gene is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in nucleotide excision repair (NER). This protein was shown to interact with, and elevate the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), which suggested a role in DNA damage recognition in base excision repair. This protein contains an N-terminal ubiquitin-like domain, which was reported to interact with 26S proteasome, as well as with ubiquitin protein ligase E6AP, and thus suggests that this protein may be involved in the ubiquitin mediated proteolytic pathway in cells.
Alias Symbols: HHR23A, MGC111083
Protein Interaction Partner: ATXN3,EP300,ATXN3,ATXN7,EP300,EWSR1,MPG,PDE6D,PSMD4,RPN1,SQSTM1,TRAF2,UBB,UBL7,UBQLN4,XPC,ATXN3,EWSR1,OTUD1,PDE6D,PSMD4,SQSTM1,TRAF2,UBI4,UBL7,XPC
Protein Size: 363 -
分子量
- 40 kDa
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基因ID
- 5886
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NCBI登录号
- NM_005053, NP_005044
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UniProt
- P54725
抗原
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