This is a synthetic peptide designed for use in combination with anti-RABGEF1 antibody (Catalog #: ARP55073_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
RABGEF1 forms a complex with rabaptin-5 (RABPT5, MIM 603616) that is required for endocytic membrane fusion, and it serves as a specific guanine nucleotide exchange factor (GEF) for RAB5 (RAB5A, MIM 179512) (Horiuchi et al., 1997 [PubMed 9323142]).
Alias Symbols: FLJ32302, RABEX5, rabex-5
Protein Interaction Partner: AP1G1,C19orf50,GGA1,GGA2,RAB33B,RAB4A,RABEP1,RNF11,RNF168,RPS27A,UBB,YWHAB,C19orf50,GGA1,YWHAB,YWHAG