Pyrin and HIN Domain Family, Member 1 (PYHIN1) Peptide
PYHIN1
适用: 人
宿主: 合成
BP, WB
产品编号 ABIN982510
发货至:
中国
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Contact Info
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中国
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Quick Overview for Pyrin and HIN Domain Family, Member 1 (PYHIN1) Peptide (ABIN982510)
抗原
PYHIN1
(Pyrin and HIN Domain Family, Member 1 (PYHIN1))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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产品特性
- This is a synthetic peptide designed for use in combination with anti-PYHIN1 antibody (Catalog #: ARP50875_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- PYHIN1 (Pyrin and HIN Domain Family, Member 1 (PYHIN1))
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背景
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PYHIN1 belongs to the HIN-200 family. This protein is major mediator of the tumor suppressor activity of IFN in breast cancer cells. It promotes ubiquitination and subsequent degradation of MDM2, which leads to p53/TP53 stabilization, and HDAC1, which in turn enhances maspin expression, and impairs invasive activity of cancer cells.
Alias Symbols: IFIX, MGC23885, RP11-520H16.1
Protein Size: 492 -
分子量
- 55 kDa
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基因ID
- 149628
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NCBI登录号
- NM_152501, NP_689714
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UniProt
- Q6K0P9
抗原
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