This is a synthetic peptide designed for use in combination with anti-PVRL3 antibody (Catalog #: ARP42446_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Nectins (e.g., PVRL1, MIM 600644) are immunoglobulin-like adhesion molecules that interact with afadin (AF6, MIM 159559). Afadin is an actin filament-binding protein that connects nectins to the actin cytoskeleton. The nectin-afadin system organizes adher