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Poliovirus Receptor-Related 1 (Herpesvirus Entry Mediator C) (PVRL1) (N-Term) Peptide

PVRL1 适用: 人 宿主: 合成 BP, WB
产品编号 ABIN982488
发货至: 中国
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Quick Overview for Poliovirus Receptor-Related 1 (Herpesvirus Entry Mediator C) (PVRL1) (N-Term) Peptide (ABIN982488)

抗原

PVRL1 (Poliovirus Receptor-Related 1 (Herpesvirus Entry Mediator C) (PVRL1))

宿主

资源

  • 2
合成

应用范围

Blocking Peptide (BP), Western Blotting (WB)
  • 蛋白结构域

    N-Term

    序列

    QLNLTVMAKP TNWIEGTQAV LRAKKGQDDK VLVATCTSAN GKPPSVVSWE

    产品特性

    This is a synthetic peptide designed for use in combination with anti-PVRL1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    纯化方法

    Purified
  • 应用备注

    Each Investigator should determine their own optimal working dilution for specific applications.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    浓度

    1 mg/mL

    缓冲液

    Final peptide concentration is 1 mg/mL in PBS.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原

    PVRL1 (Poliovirus Receptor-Related 1 (Herpesvirus Entry Mediator C) (PVRL1))

    背景

    This gene encodes an adhesion protein that plays a role in the organization of adherens junctions and tight junctions in epithelial and endothelial cells. The protein is a calcium(2+)-independent cell-cell adhesion molecule that belongs to the immunoglobulin superfamily and has 3 extracellular immunoglobulin-like loops, a single transmembrane domain (in some isoforms), and a cytoplasmic region. This protein acts as a receptor for glycoprotein D (gD) of herpes simplex viruses 1 and 2 (HSV-1, HSV-2), and pseudorabies virus (PRV) and mediates viral entry into epithelial and neuronal cells. Mutations in this gene cause cleft lip and palate/ectodermal dysplasia 1 syndrome (CLPED1) as well as non-syndromic cleft lip with or without cleft palate (CL/P). Alternative splicing results in multiple transcript variants encoding proteins with distinct C-termini.

    Alias Symbols: CD111, CLPED1, ED4, HIgR, HVEC, MGC142031, MGC16207, OFC7, PRR, PRR1, PVRR, PVRR1, SK-12, nectin-1

    Protein Size: 517

    分子量

    57 kDa

    基因ID

    5818

    NCBI登录号

    NM_002855, NP_002846

    UniProt

    Q15223
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