PURA
(Purine-Rich Element Binding Protein A (PURA))
蛋白结构域
N-Term
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
产品特性
This is a synthetic peptide designed for use in combination with anti-PURA antibody (Catalog #: ARP38688_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Each Investigator should determine their own optimal working dilution for specific applications.
限制
仅限研究用
状态
Lyophilized
溶解方式
Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
浓度
1 mg/mL
缓冲液
Final peptide concentration is 1 mg/mL in PBS.
注意事项
Avoid repeated freeze-thaw cycles.
储存条件
-20 °C
储存方法
For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
抗原
PURA
(Purine-Rich Element Binding Protein A (PURA))
别名
CAGER-1 Peptide, Pur-alpha Peptide, ssCRE-BP Peptide, PUR-ALPHA Peptide, PUR1 Peptide, PURALPHA Peptide, zgc:103411 Peptide, pur-alpha Peptide, pur1 Peptide, puralpha Peptide, purine-rich element binding protein A Peptide, purine rich element binding protein A Peptide, purine-rich element binding protein Aa Peptide, purine-rich element binding protein A L homeolog Peptide, pura Peptide, Pura Peptide, PURA Peptide, puraa Peptide, pura.L Peptide
背景
PURA is a sequence-specific, single-stranded DNA-binding protein. It binds preferentially to the single strand of the purine-rich element termed PUR, which is present at origins of replication and in gene flanking regions in a variety of eukaryotes from yeasts through humans. Thus, it is implicated in the control of both DNA replication and transcription. Deletion of this gene has been associated with myelodysplastic syndrome and acute myelogenous leukemia.This gene product is a sequence-specific, single-stranded DNA-binding protein. It binds preferentially to the single strand of the purine-rich element termed PUR, which is present at origins of replication and in gene flanking regions in a variety of eukaryotes from yeasts through humans. Thus, it is implicated in the control of both DNA replication and transcription. Deletion of this gene has been associated with myelodysplastic syndrome and acute myelogenous leukemia. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: PUR-ALPHA, PUR1, PURALPHA
Protein Interaction Partner: Jvgp5,YBX1,ADAP1,CCNT1,CDK5,E2F1,PURB,RB1,SP1,YBX1,CCNT1,CNBP,E2F1,HNRNPA1,MEPCE,SP1