Poly-U Binding Splicing Factor 60KDa (PUF60) Peptide
PUF60
适用: 人
宿主: 合成
BP, IHC, WB
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- 抗原 See all PUF60 products
- PUF60 (Poly-U Binding Splicing Factor 60KDa (PUF60))
- 宿主
- 人
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资源
- 合成
- 应用范围
- Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
- 产品特性
- This is a synthetic peptide designed for use in combination with anti-PUF60 antibody (Catalog #: ARP40760_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- 纯化方法
- Purified
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- 应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 浓度
- 1 mg/mL
- 缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- 抗原
- PUF60 (Poly-U Binding Splicing Factor 60KDa (PUF60))
- 背景
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PUF60 is a Ro RNP-binding protein. It interacts with Ro RNPs and their interaction is thought to represent a gain of function for Ro RNPs. This protein also forms a ternary complex with far upstream element (FUSE) and FUSE-binding protein. It can repress a c-myc reporter via the FUSE. It is also known to target transcription factor IIH and inhibit activated transcription.The protein encoded by this gene is a Ro RNP-binding protein. It interacts with Ro RNPs and their interaction is thought to represent a gain of function for Ro RNPs. This protein also forms a ternary complex with far upstream element (FUSE) and FUSE-binding protein. It can repress a c-myc reporter via the FUSE. It is also known to target transcription factor IIH and inhibit activated transcription. This gene is implicated in the xeroderma pigmentosum disorder. There are two alternatively spliced transcript variants of this gene encoding different isoforms. There seems to be evidence of multiple polyadenylation sites for this gene.The protein encoded by this gene is a Ro RNP-binding protein. It interacts with Ro RNPs and their interaction is thought to represent a gain of function for Ro RNPs. This protein also forms a ternary complex with far upstream element (FUSE) and FUSE-binding protein. It can repress a c-myc reporter via the FUSE. It is also known to target transcription factor IIH and inhibit activated transcription. This gene is implicated in the xeroderma pigmentosum disorder. There are two alternatively spliced transcript variants of this gene encoding different isoforms. There seems to be evidence of multiple polyadenylation sites for this gene.
Alias Symbols: FIR, FLJ31379, RoBPI, SIAHBP1
Protein Interaction Partner: CD101,CHD3,FUBP1,LOH12CR1,PCBP1,PPP1R16A,PUF60,SAP30BP,SRSF11,U2AF2,VIM,YWHAG,CD2BP2,CHD3,DDX3X,ELAC2,EWSR1,G3BP1,GPN1,HNRNPA3,HNRNPC,HNRNPL,IGF2BP1,IGF2BP2,IGF2BP3,ILK,KHSRP,LOH12CR1,MOV10,OLA1,P4HB,PABPC1,PABPC4,PPP1R16A,PUF60,RNMTL1,RNPS1,SAP30BP,SARS2,SF3A2,SF3A3,SF3B1,SRSF11,SSB,STOM,SYNCRIP,TROVE2,TTN,U2AF2,UGP2,VIM
Protein Size: 542 - 分子量
- 58 kDa
- 基因ID
- 22827
- NCBI登录号
- NM_014281, NP_055096
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