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Pancreas Specific Transcription Factor, 1a (PTF1A) (N-Term) Peptide

PTF1A 适用: 人 宿主: 合成 BP, WB
产品编号 ABIN982418
发货至: 中国
  • 抗原 See all PTF1A products
    PTF1A (Pancreas Specific Transcription Factor, 1a (PTF1A))
    蛋白结构域
    N-Term
    宿主
    资源
    • 6
    合成
    应用范围
    Blocking Peptide (BP), Western Blotting (WB)
    产品特性
    This is a synthetic peptide designed for use in combination with anti-PTF1A antibody (Catalog #: ARP32531_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    纯化方法
    Purified
  • 应用备注
    Each Investigator should determine their own optimal working dilution for specific applications.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    浓度
    1 mg/mL
    缓冲液
    Final peptide concentration is 1 mg/mL in PBS.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原
    PTF1A (Pancreas Specific Transcription Factor, 1a (PTF1A))
    别名
    PTF1A Peptide, PTF1 Peptide, si:zc142h2.2 Peptide, zgc:112216 Peptide, Ptf1a/p48 Peptide, XPtf1a Peptide, PTF1-p48 Peptide, bHLHa29 Peptide, PTF1p48 Peptide, pancreas specific transcription factor, 1a Peptide, PTF1A Peptide, ptf1a Peptide, Ptf1a Peptide
    背景
    PTF1A is a pancreas specific transcription factor. Mammalian studies have implicated important roles for the basic helix-loop-helix transcription factor PTF1A-p48 in the development of both exocrine and endocrine pancreas. This gene encodes a protein that is a component of the pancreas transcription factor 1 complex (PTF1) and is known to have a role in mammalian pancreatic development. The protein plays a role in determining whether cells allocated to the pancreatic buds continue towards pancreatic organogenesis or revert back to duodenal fates. The protein is thought to be involved in the maintenance of exocrine pancreas-specific gene expression including elastase 1 and amylase. Mutations in this gene cause cerebellar agenesis and loss of expression is seen in ductal type pancreas cancers. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

    Alias Symbols: PTF1-p48, bHLHa29

    Protein Interaction Partner: TCF12

    Protein Size: 328
    分子量
    35 kDa
    基因ID
    256297
    NCBI登录号
    NM_178161, NP_835455
    UniProt
    Q7RTS3
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