Presenilin Enhancer 2 Homolog (PSENEN) (C-Term) Peptide
PSENEN
适用: 人
宿主: 合成
BP, WB
产品编号 ABIN982323
发货至:
中国
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Contact Info
Our Local Distributor
中国
北京 101111
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
Quick Overview for Presenilin Enhancer 2 Homolog (PSENEN) (C-Term) Peptide (ABIN982323)
抗原
PEN2 (PSENEN)
(Presenilin Enhancer 2 Homolog (PSENEN))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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蛋白结构域
- C-Term
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序列
- SQIKGYVWRS AVGFLFWVIV LTSWITIFQI YRPRWGALGD YLSFTIPLGT
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产品特性
- This is a synthetic peptide designed for use in combination with anti-PSENEN Antibody(ARP59439_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- PEN2 (PSENEN) (Presenilin Enhancer 2 Homolog (PSENEN))
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背景
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Presenilins, which are components of the gamma-secretase protein complex, are required for intramembranous processing of some type I transmembrane proteins, such as the Notch proteins and the beta-amyloid precursor protein. Signaling by Notch receptors mediates a wide range of developmental cell fates. Processing of the beta-amyloid precursor protein generates neurotoxic amyloid beta peptides, the major component of senile plaques associated with Alzheimer's disease. This gene encodes a protein that is required for Notch pathway signaling, and for the activity and accumulation of gamma-secretase.
Alias Symbols: MDS033, MSTP064, PEN-2, PEN2
Protein Interaction Partner: APH1A,NCSTN,PSEN1,APH1A,NCSTN,PSEN1,PSEN2,TMED10,APH1A,NCSTN,PSEN1,PSEN2
Protein Size: 101 -
分子量
- 12 kDa
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基因ID
- 55851
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NCBI登录号
- NM_172341, NP_758844
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UniProt
- Q9NZ42
抗原
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