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Cytohesin 4 (CYTH4) (N-Term) Peptide

CYTH4 适用: 人 宿主: 合成 BP, WB
产品编号 ABIN982317
发货至: 中国

Quick Overview for Cytohesin 4 (CYTH4) (N-Term) Peptide (ABIN982317)

抗原

Cytohesin 4 (CYTH4)

宿主

资源

  • 7
合成

应用范围

Blocking Peptide (BP), Western Blotting (WB)
  • 蛋白结构域

    N-Term

    产品特性

    This is a synthetic peptide designed for use in combination with anti-PSCD4 antibody (Catalog #: ARP54947_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    纯化方法

    Purified
  • 应用备注

    Each Investigator should determine their own optimal working dilution for specific applications.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    浓度

    1 mg/mL

    缓冲液

    Final peptide concentration is 1 mg/mL in PBS.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原

    Cytohesin 4 (CYTH4)

    背景

    PSCD4 promotes guanine-nucleotide exchange on ARF1 and ARF5. PSCD4 promotes the activation of ARF through replacement of GDP with GTP.Pleckstrin homology, Sec7 and coiled/coil domains 4 (PSCD4) is a member of the PSCD family. Members of this family have identical structural organization that consists of an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein (GEP) activity, and the PH domain interacts with phospholipids and is responsible for association of PSCDs with membranes. Members of this family appear to mediate the regulation of protein sorting and membrane trafficking. The PSCD4 exhibits GEP activity in vitro with both ARF1 and ARF5 but is inactive with ARF6. The PSCD4 and PSCD1 gene structures are very similar.

    Alias Symbols: CYT4, DJ63G5.1, PSCD4

    Protein Interaction Partner: IPCEF1

    Protein Size: 394

    分子量

    46 kDa

    基因ID

    27128

    NCBI登录号

    NM_013385, NP_037517

    UniProt

    Q9UIA0
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