Protein Kinase C, eta (PRKCH) (N-Term) Peptide
PRKCH
适用: 人
宿主: 合成
BP, WB
产品编号 ABIN982217
发货至:
中国
Contact our Customer Service for availability and price in your country.
Contact Info
Our Local Distributor
中国
北京 101111
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
Quick Overview for Protein Kinase C, eta (PRKCH) (N-Term) Peptide (ABIN982217)
抗原
PKC eta (PRKCH)
(Protein Kinase C, eta (PRKCH))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
-
-
蛋白结构域
- N-Term
-
序列
- KKGHQLLDPY LTVSVDQVRV GQTSTKQKTN KPTYNEEFCA NVTDGGHLEL
-
产品特性
- This is a synthetic peptide designed for use in combination with anti-PRKCH Antibody(ARP56703_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
-
纯化方法
- Purified
-
-
-
-
应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
-
浓度
- 1 mg/mL
-
缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
-
注意事项
- Avoid repeated freeze-thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
-
- PKC eta (PRKCH) (Protein Kinase C, eta (PRKCH))
-
背景
-
Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. It is a calcium-independent and phospholipids-dependent protein kinase. It is predominantly expressed in epithelial tissues and has been shown to reside specifically in the cell nucleus. This protein kinase can regulate keratinocyte differentiation by activating the MAP kinase MAPK13 (p38delta)-activated protein kinase cascade that targets CCAAT/enhancer-binding protein alpha (CEBPA). It is also found to mediate the transcription activation of the transglutaminase 1 (TGM1) gene.
Alias Symbols: MGC26269, MGC5363, PKC-L, PKCL, PRKCL, nPKC-eta
Protein Interaction Partner: AKAP13,PDPK1,PRKCH,PRKD1,CDK2,FYN,ITGB2,NUMB,PARD6A,PRKD1,PTPN11,SRC,CDK2,ZBTB8OS
Protein Size: 683 -
分子量
- 78 kDa
-
基因ID
- 5583
-
NCBI登录号
- NM_006255, NP_006246
-
UniProt
- P24723
抗原
-
You are here:
