Protein Kinase, AMP-Activated, gamma 3 Non-Catalytic Subunit (PRKAG3) (N-Term) Peptide
PRKAG3
适用: 人
宿主: 合成
BP, WB
Quick Overview for Protein Kinase, AMP-Activated, gamma 3 Non-Catalytic Subunit (PRKAG3) (N-Term) Peptide (ABIN982211)
抗原
PRKAG3
(Protein Kinase, AMP-Activated, gamma 3 Non-Catalytic Subunit (PRKAG3))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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蛋白结构域
- N-Term
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序列
- ENSSSWPSPA VTSSSERIRG KRRAKALRWT RQKSVEEGEP PGQGEGPRSR
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产品特性
- This is a synthetic peptide designed for use in combination with anti-PRKAG3 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- PRKAG3 (Protein Kinase, AMP-Activated, gamma 3 Non-Catalytic Subunit (PRKAG3))
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背景
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The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit is one of the gamma regulatory subunits of AMPK. It is dominantly expressed in skeletal muscle. Studies of the pig counterpart suggest that this subunit may play a key role in the regulation of energy metabolism in skeletal muscle.
Alias Symbols: AMPKG3
Protein Interaction Partner: PRKAA1,PRKAB1,PRKAB2
Protein Size: 489 -
分子量
- 54 kDa
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基因ID
- 53632
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NCBI登录号
- NM_017431, NP_059127
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UniProt
- Q9UGI9
抗原
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