Protein Phosphatase 1, Regulatory Subunit 8 (PPP1R8) Peptide
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Quick Overview for Protein Phosphatase 1, Regulatory Subunit 8 (PPP1R8) Peptide (ABIN982115)
抗原
宿主
资源
应用范围
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产品特性
- This is a synthetic peptide designed for use in combination with anti-PPP1R8 antibody (Catalog #: ARP40753_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- PPP1R8 (Protein Phosphatase 1, Regulatory Subunit 8 (PPP1R8))
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背景
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This gene, through alternative splicing, encodes three different isoforms. Two of the protein isoforms encoded by this gene are specific inhibitors of type 1 serine/threonine protein phosphatases and can bind but not cleave RNA. The third protein isoform lacks the phosphatase inhibitory function but is a single-strand endoribonuclease comparable to RNase E of E. coli. This isoform requires magnesium for its function and cleaves specific sites in A+U-rich regions of RNA.This gene, through alternative splicing, encodes three different isoforms. Two of the protein isoforms encoded by this gene are specific inhibitors of type 1 serine/threonine protein phosphatases and can bind but not cleave RNA. The third protein isoform lacks the phosphatase inhibitory function but is a single-strand endoribonuclease comparable to RNase E of E. coli. This isoform requires magnesium for its function and cleaves specific sites in A+U-rich regions of RNA.This gene, through alternative splicing, encodes three different isoforms. Two of the protein isoforms encoded by this gene are specific inhibitors of type 1 serine/threonine protein phosphatases and can bind but not cleave RNA. The third protein isoform lacks the phosphatase inhibitory function but is a single-strand endoribonuclease comparable to RNase E of E. coli. This isoform requires magnesium for its function and cleaves specific sites in A+U-rich regions of RNA.
Alias Symbols: ARD1, ARD-1, NIPP1, NIPP-1, PRO2047
Protein Interaction Partner: C14orf1,C7orf64,CDC5L,CRMP1,CSNK2A1,CSNK2A2,EED,GBP2,HDAC2,LYN,MELK,PPP1CA,PPP1CC,PRKACA,SETDB1,SF3B1,STC2,C14orf1,C7orf64,CRMP1,EED,GBP2,HDAC2,LYN,NME2,PPP1CA,PPP1CB,PPP1CC,PRKACA,SETDB1,SF3B1,STC2
Protein Size: 351 -
分子量
- 39 kDa
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基因ID
- 5511
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NCBI登录号
- NM_014110, NP_054829
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UniProt
- Q12972
抗原
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