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Peptidylprolyl Isomerase A (Cyclophilin A) (PPIA) Peptide

PPIA 适用: 人 宿主: 合成 BP, WB, IHC
产品编号 ABIN982060
发货至: 中国
  • 抗原 See all PPIA products
    PPIA (Peptidylprolyl Isomerase A (Cyclophilin A) (PPIA))
    宿主
    资源
    • 8
    合成
    应用范围
    Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
    产品特性
    This is a synthetic peptide designed for use in combination with anti-PPIA antibody (Catalog #: ARP51352_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    纯化方法
    Purified
  • 应用备注
    Each Investigator should determine their own optimal working dilution for specific applications.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    浓度
    1 mg/mL
    缓冲液
    Final peptide concentration is 1 mg/mL in PBS.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原
    PPIA (Peptidylprolyl Isomerase A (Cyclophilin A) (PPIA))
    背景
    PPIA is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. PPIA is a cyclosporin binding-protein and may play a role in cyclosporin A-mediated immunosuppression. The protein can also interact with several HIV proteins, including p55 gag, Vpr, and capsid protein, and has been shown to be necessary for the formation of infectious HIV virions.The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein is a cyclosporin binding-protein. It may play a role in cyclosporin A-mediated immunosuppression. This protein can interact with several HIV proteins including p55 gag, Vpr, and capsid protein. It has been shown to be necessary for the formation of infectious HIV virions. Multiple pseudogenes that map to different chromosomes have been reported. Three alternatively spliced transcript variants encoding two distinct isoforms have been observed.

    Alias Symbols: CYPA, CYPH, MGC117158, MGC12404, MGC23397

    Protein Interaction Partner: E2F4,CD99,RB1,env,nef,vif,BSG,CD99,ITK,JAK2,PPIA,PPP3R1,PRLR,PRR13,PRSS23,PTPRN,RB1,S100A8,SUPT5H,ITK,JAK2,N,PPP3CA,PPP3R1,PRLR,PRR13,PRSS23,S100A8,Supt5h,YY1

    Protein Size: 165
    分子量
    18 kDa
    基因ID
    5478
    NCBI登录号
    NM_021130, NP_066953
    UniProt
    P62937
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