POU Domain, Class 4, Transcription Factor 3 (POU4F3) Peptide
Our Local Distributor
北京 101111
Quick Overview for POU Domain, Class 4, Transcription Factor 3 (POU4F3) Peptide (ABIN982016)
抗原
宿主
资源
应用范围
-
-
产品特性
- This is a synthetic peptide designed for use in combination with anti-POU4F3 antibody (Catalog #: ARP33065_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
-
纯化方法
- Purified
-
-
-
-
应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
-
浓度
- 1 mg/mL
-
缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
-
注意事项
- Avoid repeated freeze-thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
-
- POU4F3 (POU Domain, Class 4, Transcription Factor 3 (POU4F3))
-
背景
-
POU4F3 is capable of activating both BDNF and NT-3 promoters in inner ear sensory epithelial cell lines. Mutant POU4F3 loses most of its transcriptional activity and most of its ability to bind to DNA. The mutation causes autosomal-dominant nonsyndromic hearing loss and eventually leads to hair cell morbidity in affected family members.
Alias Symbols: BRN3C, DFNA15
Protein Size: 338 -
分子量
- 37 kDa
-
基因ID
- 5459
-
NCBI登录号
- NM_002700, NP_002691
-
UniProt
- Q15319
抗原
-