POU Domain, Class 4, Transcription Factor 3 (POU4F3) Peptide
POU4F3
适用: 人
宿主: 合成
BP, WB, IHC
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- 抗原 See all POU4F3 products
- POU4F3 (POU Domain, Class 4, Transcription Factor 3 (POU4F3))
- 宿主
- 人
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资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- 产品特性
- This is a synthetic peptide designed for use in combination with anti-POU4F3 antibody (Catalog #: ARP33065_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- 纯化方法
- Purified
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- 应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 浓度
- 1 mg/mL
- 缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- 抗原
- POU4F3 (POU Domain, Class 4, Transcription Factor 3 (POU4F3))
- 背景
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POU4F3 is capable of activating both BDNF and NT-3 promoters in inner ear sensory epithelial cell lines. Mutant POU4F3 loses most of its transcriptional activity and most of its ability to bind to DNA. The mutation causes autosomal-dominant nonsyndromic hearing loss and eventually leads to hair cell morbidity in affected family members.
Alias Symbols: BRN3C, DFNA15
Protein Size: 338 - 分子量
- 37 kDa
- 基因ID
- 5459
- NCBI登录号
- NM_002700, NP_002691
- UniProt
- Q15319
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