Polymerase (DNA Directed) kappa (POLK) (N-Term) Peptide
POLK
适用: 人
宿主: 合成
BP, WB
产品编号 ABIN981953
发货至:
中国
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Contact Info
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中国
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Quick Overview for Polymerase (DNA Directed) kappa (POLK) (N-Term) Peptide (ABIN981953)
抗原
POLK
(Polymerase (DNA Directed) kappa (POLK))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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蛋白结构域
- N-Term
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产品特性
- This is a synthetic peptide designed for use in combination with anti-POLK antibody (Catalog #: ARP48792_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Each Investigator should determine their own optimal working dilution for specific applications.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- POLK (Polymerase (DNA Directed) kappa (POLK))
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背景
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POLK belongs to the DNA polymerase type-Y family. It contains 2 Rad18-type zinc fingers and 1 umuC domain. POLK is a DNA polymerase specifically involved in DNA repair. It plays an important role in translesion synthesis, where the normal high-fidelity DNA polymerases cannot proceed and DNA synthesis stalls. Depending on the context, it inserts the correct base, but causes frequent base transitions, transversions and frameshifts. It lacks 3'-5' proofreading exonuclease activity. POLK forms a Schiff base with 5'-deoxyribose phosphate at abasic sites, but does not have lyase activity.
Alias Symbols: DINB1, DINP, POLQ
Protein Interaction Partner: REV1,REV1
Protein Size: 870 -
分子量
- 99 kDa
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基因ID
- 51426
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NCBI登录号
- NM_016218, NP_057302
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UniProt
- Q9UBT6
抗原
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