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Paired-Like Homeodomain 2 (PITX2) Peptide

PITX2 适用: 人 宿主: 合成 BP, WB, IHC
产品编号 ABIN981799
发货至: 中国

Quick Overview for Paired-Like Homeodomain 2 (PITX2) Peptide (ABIN981799)

抗原

PITX2 (Paired-Like Homeodomain 2 (PITX2))

宿主

资源

  • 3
合成

应用范围

Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
  • 产品特性

    This is a synthetic peptide designed for use in combination with anti-PITX2 antibody (Catalog #: ARP35634_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    纯化方法

    Purified
  • 应用备注

    Each Investigator should determine their own optimal working dilution for specific applications.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    浓度

    1 mg/mL

    缓冲液

    Final peptide concentration is 1 mg/mL in PBS.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原

    PITX2 (Paired-Like Homeodomain 2 (PITX2))

    背景

    The PITX2 gene encodes a member of the RIEG/PITX homeobox family, which is in the bicoid class of homeodomain proteins. This protein acts as a transcription factor and regulates procollagen lysyl hydroxylase gene expression. Mutations in PITX2 are associated with Axenfeld-Rieger syndrome (ARS), iridogoniodysgenesis syndrome (IGDS), and sporadic cases of Peters anomaly. This protein is involved in the development of the eye, tooth and abdominal organs. It also acts as a transcriptional regulator involved in basal and hormone-regulated activity of prolactin.

    Alias Symbols: RS, RGS, ARP1, Brx1, IDG2, IGDS, IHG2, PTX2, RIEG, IGDS2, IRID2, Otlx2, RIEG1

    Protein Interaction Partner: CTNNB1,HDAC1,KAT5,LEF1,PDLIM1,PITX2,PROP1,HERC5,MSX2,PITX2,Pou1f1,TRIM25

    Protein Size: 324

    分子量

    36 kDa

    基因ID

    5308

    NCBI登录号

    NM_000325, NP_000316
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