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Peptidase Inhibitor 3, Skin-Derived (PI3) (N-Term) Peptide

PI3 适用: 人 宿主: 合成 BP, WB
产品编号 ABIN981719
发货至: 中国

Quick Overview for Peptidase Inhibitor 3, Skin-Derived (PI3) (N-Term) Peptide (ABIN981719)

抗原

PI3 (Peptidase Inhibitor 3, Skin-Derived (PI3))

宿主

资源

  • 3
合成

应用范围

Blocking Peptide (BP), Western Blotting (WB)
  • 蛋白结构域

    N-Term

    产品特性

    This is a synthetic peptide designed for use in combination with anti-PI3 antibody (Catalog #: ARP45340_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    纯化方法

    Purified
  • 应用备注

    Each Investigator should determine their own optimal working dilution for specific applications.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    浓度

    1 mg/mL

    缓冲液

    Final peptide concentration is 1 mg/mL in PBS.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原

    PI3 (Peptidase Inhibitor 3, Skin-Derived (PI3))

    背景

    PI3 is an elastase-specific inhibitor that functions as an antimicrobial peptide against Gram-positive and Gram-negative bacteria. PI3 contains a WAP-type four-disulfide core (WFDC) domain, and is thus a member of the WFDC domain family. Most WFDC gene members are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. PI3 belongs to the centromeric cluster. Expression of this gene is upgulated by bacterial lipopolysaccharides and cytokines.This gene encodes an elastase-specific inhibitor, which contains a WAP-type four-disulfide core (WFDC) domain, and is thus a member of the WFDC domain family. Most WFDC gene members are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. This gene belongs to the centromeric cluster. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

    Alias Symbols: ESI, MGC13613, SKALP, WAP3, WFDC14, cementoin

    Protein Interaction Partner: CELA1,EVPL,CSTA,KRT1,LOR

    Protein Size: 117

    分子量

    6 kDa

    基因ID

    5266

    NCBI登录号

    NM_002638, NP_002629

    UniProt

    P19957
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